Fig. 4: percentage of late-differentiated effector memory (EM) CD8+ T-lymphocyte expressing Vβ2 (A) and Vβ22 (B) and of central memory (CM) CD8+ T-lymphocyte expressing Vβ2 (C) and Vβ13.2 (D). Statistical analyses were performed by Mann-Whitney U test. Results were considered significant when p < 0.05. Each point represents one subject. HS: healthy subjects (n = 18); PAD: patients with active disease (n = 14); PCC: patients clinically cured (n = 11); **: p < 0.01; ***: p <0.001.