TABLE I. Frequencies of mutated rpoB gene found in 53 multidrug-resistant isolates of Mycobacterium tuberculosis .

Amino acid change	Nucleotide change	Strains (n)
S531L	TCG → TTG	31
S531W	TCG → TGG	11
H526Y	CAC → TAC	3
H526D	CAC → GAC	2
D516V	GAC → GTC	1
F505V/D516F	TTC → GTC/GAC → TTC	1
S512G/H526N	AGC → GGC/CAC → AAC	1
I572V	ATC → GTC	1
No mutation	-	2