TABLE II. Effects of Corynebacterium diphtheriae CDCE8392_0813 gene interruption on human cells interactions and on susceptibility to hydrogen peroxide.
| Strain | HA titre | Human epithelial type
2 epithelial cell |
H2O2 inhibition halo (mm) | |||
|---|---|---|---|---|---|---|
| Adherence pattern | Bacteria in supernatant (CFU mL1-) | Adherent bacteria (CFU mL1-) | Internalised bacteria (CFU mL1-) | |||
| LDCIC-L1 | 32 | DA | 11.8 x 104 ± 2.23 | 5.8 x 104 ± 1.94 | 7.0 x 102 ± 0.05a | 24.75 ± 0.64a |
| CDC-E8392 | 32 | DA | 11.3 x 104 ± 1.11 | 5.3 x 104 ± 1.30 | 10.0 x 102 ± 0.57 | 22.00 ± 0.82 |
a: p < 0.05 according to unpaired ttest; CFU: colony forming units; DA: diffuse adherence; HA: agglutination of human erythrocytes (type B).