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. 2015 Jul 27;6(9):987–992. doi: 10.1021/acsmedchemlett.5b00193

Table 3. Cell Signaling: Inhibition of p-EGFR by MSDa.

compd H1975 IC50 (nM) HCC827 IC50 (nM) A431 IC50 (nM)
AZD9291 15 6 348
1 3 3 50
14 4 12 386
23 6 12 521
24 4 9 1054
a

Data represent an average of at least two separate determinations. Standard deviations are reported in the Supporting Information and vary by less than ±50%.