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. 2015 Jul 27;6(9):977–981. doi: 10.1021/acsmedchemlett.5b00159

Table 3. Pharmacokinetic Parameters of 5oa.

pharmacokinetic parameters compound 5o
Tmax (h) 2.17 ± 0.36
Cmax (μM) 2.05 ± 0.26
T1/2 (h) 2.93 ± 0.60
AUC0–24 h (μM·h) 18.98 ± 2.49
AUC0-∞ (μM·h) 19.12 ± 2.64
a

The data represent mean ± SD (n = 5). Tmax, time to reach maximal plasma concentration; Cmax, maximal plasma concentration; T1/2, elimination half-life; AUC0–24, area under the curve of plasma concentration from time 0 to 24 h; AUC0-∞, area under the curve of plasma concentration from time 0 to infinity.