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. 2015 Aug 6;6(9):993–997. doi: 10.1021/acsmedchemlett.5b00208

Table 2. Half-Lives in Human (HLM) and Mouse (MLM) Liver Microsomes.

    t1/2 (min)
compd ID HLM MLM
class I 2 38.9 ± 3.4 2.1 ± 1.1
13 30.7 ± 2.6 2.0 ± 0.8
class II 41 33.1 ± 4.8 10.5 ± 1.8
42 45.4 ± 3.0 16.1 ± 4.4
43 56.3 ± 2.3 27.7 ± 6.1