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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: J Immunol. 2015 Jun 24;195(3):806–809. doi: 10.4049/jimmunol.1500540

Figure 2. IL15 deficiency delays the development of autoimmune disease in TLR7tg mice.

Figure 2

(A) Numbers of splenic NK1.1+CD11c+ cells in each genotype shown, at least three mice per group. **p<0.01(Student t-test); (B) Survival curve for TLR7tg, TLR7tg.IL15−/− and TLR7tg.IFNαβR1−/− mice, 15 mice per group. (C ) Glomerular damage in kidney and liver inflammation scores measured as described in methods; Mice of the genotype shown, were analyzed for number of platelets (D), total serum IgG and anti-RNA IgG antibodies (E), spleen weight (F), splenocyte count (G); Data collected from three experiments with three mice per group. Asterisk represents p≤ 0.05 in Anova statistical analysis and Kaplan-Meier for survival curve.