Table 3.
Mean (standard error) demographic, psychiatric, medical, and HIV disease characteristics across HCV groups.
| HCV− (n = 120) | HCV+ (n = 26) | p | Group Difference | |
|---|---|---|---|---|
| Age (years) | 46.8(1.3) | 52.0(1.3) | .069 | -- |
| Education (years) | 14.3(0.2) | 13.0(0.5) | .006 | HCV− > HCV+ |
| Ethnicity (%) | -- | -- | ||
| African-American | 17.5 | 34.6 | ||
| Asian | 2.5 | 0.0 | ||
| Hispanic | 15.8 | 15.4 | ||
| White | 64.2 | 50.0 | ||
| Gender (% men) | 76.7 | 73.1 | -- | -- |
| Estimated Verbal IQ (WTAR) | 104.3(0.9) | 99.8(1.7) | .039 | HCV− > HCV+ |
| POMS total (of 200) | 49.2(3.2) | 55.4(7.4) | -- | -- |
| Major Depressiona (%) | 53.3 | 65.4 | -- | -- |
| Generalized Anxietya (%) | 10.0 | 30.77 | .010 | HCV− < HCV+ |
| Substance Dependenceb (%) | 47.5 | 80.77 | .002 | HCV− < HCV+ |
| HIV Infection c (%) | 53.33 | 73.1 | .082 | -- |
| Estimated Duration of Infection c (months) | 157.5(12.7) | 195.9(18.9) | -- | -- |
| AIDS c (%) | 54.7 | 68.4 | -- | -- |
| CD4 count c (cells/μL) | 559.6(33.9) | 550.5(51.4) | -- | -- |
| Nadir CD4 c (cells/μL) | 198.1(19.7) | 208.8(36.4) | -- | -- |
| cART status c (%) | 89.1 | 84.2 | -- | -- |
| Plasma RNA detectable c (%) | 24.2 | 22.2 | -- | -- |
| Among subjects on cART (%) | 14.6 | 20.0 | -- | -- |
Note. HCV = Hepatitis C virus; WTAR = Wechsler Test of Adult Reading; POMS = Profile of Mood States; AIDS = Acquired Immune Deficiency Syndrome; CD4 = Cluster of Differentiation 4; cART = combination antiretroviral therapy.
a
Includes both current (e.g., the last 30 days) and lifetime diagnosis.
b
Any lifetime diagnosis of dependence on alcohol or illicit substances.
c
Sample size for HIV disease characteristic variables: HCV− n=64, HCV+ n=19.