Figure 2.

Levels of CD4⁺CD57⁺, CD4⁺CD57⁺CD28⁺, CD4⁺CD25⁺ and CD8⁺CD25⁺ T cells are higher after surgery in GBM patients than in healthy controls (HC). T-cell phenotype was analyzed in PBMCs from GBM patients before and 3, 12, and 24 weeks after surgery. (A) Levels of CD4⁺CD57⁺ T cells were higher in GBM patients at all-time points compared to HC. (B–D) Levels of CD8⁺CD57⁺, CD4⁺CD57⁺CD28⁻, and CD8⁺CD57⁺CD28⁻T cells did not differ. (E) Levels of CD4⁺CD57⁺CD28⁺ T cells were higher in GBM patients than in controls at all-time points. (F) Levels of CD8⁺CD57⁺CD28⁺ T did not differ. (G) Levels of CD4⁺CD25⁺T cells were lower at baseline and 3 weeks after surgery. (H) Levels of CD8⁺CD25⁺T cells were lower at 24 weeks after surgery.