Table 4.

Linear regression analysis comparing patient cohorts with Valcyte treatment versus placebo

CD 3 cells	Regression coefficient	p value
0 weeks	−0.1510336	0.2173
3 weeks	0.139136	0.4
12 weeks	−0.1315498	0.3092
24 weeks	−0.0630347	0.8129
CD 4+ cells
0 weeks	−0.0385455	0.6983
3 weeks	−0.0523832	0.5933
12 weeks	0.0612635	0.5189
24 weeks	−0.0246153	0.7993
CD 8+ cells
0 weeks	0.1092555	0.4089
3 weeks	0.3792077	0.0462
12 weeks	0.00146	0.9925
24 weeks	0.205801	0.2462
GD T cells
0 weeks	−0.4969697	0.0891
3 weeks	−0.3266768	0.3045
12 weeks	0.0294959	0.9175
24 weeks	−0.0437197	0.8812
CD 4/CD 57 cells
0 weeks	−0.2710945	0.3597
3 weeks	−0.1967002	0.5725
12 weeks	0.2718693	0.3706
24 weeks	−0.4021137	0.1652
CD 8/CD 57 cells
0 weeks	0.1518069	0.6128
3 weeks	−0.1124162	0.6826
12 weeks	−0.0695953	0.8608
24 weeks	−0.2129092	0.4692
CD 4/CD 28null cells
0 weeks	0.312091	0.3743
3 weeks	−0.5047389	0.1493
12 weeks	−0.0089941	0.9803
24 weeks	−0.4274857	0.1648
CD 8/CD 28null cells
0 weeks	0.1306234	0.6972
3 weeks	0.0858196	0.8044
12 weeks	−0.0895841	0.6666
24 weeks	−0.4305437	0.1522
CD 4/ CD57/CD 28null cells
0 weeks	1.110387	0.0673
3 weeks	1.203756	0.058
12 weeks	0.1420544	0.7847
24 weeks	0.5643537	0.3595
CD 8/ CD57/CD 28null cells
0 weeks	−0.0155809	0.9756
3 weeks	−0.6119404	0.137
12 weeks	0.3224287	0.3278
24 weeks	−0.6235189	0.1541
CD 4/CD 25 cells
0 weeks	−0.21233	0.6179
3 weeks	0.7711318	0.0947
12 weeks	0.4433576	0.1565
24 weeks	0.1041078	0.7244
CD 8/CD 25 cells
0 weeks	0.1311385	0.7944
3 weeks	0.2672356	0.5469
12 weeks	0.6383185	0.2732
24 weeks	0.0276734	0.9453