Table 2.

Biochemical Evaluation by Vitamin D Status

	Normal	25OHD, ng/mL			P Value
		<20	20–29	≥30
n		19	36	45
25OHD, ng/mL	30–100	13.5 ± 1.1	25.5 ± 0.8	37.9 ± 0.7	N/A
1,25-dihydroxyvitamin D, pg/mL	18–72	77.3 ± 5.5	73.2 ± 4.1	63.3 ± 3.6	.06
Serum calcium, mg/dL	8.6–10.2	10.8 ± 0.1	10.7 ± 0.1	10.6 ± 0.1	.32
Serum PTH, pg/mL	14–66	126 ± 10	81 ± 7a	72 ± 7b	<.0001
Phosphate, mg/dL	2.7–4.5	2.8 ± 0.1	3.0 ± 0.1c	3.2 ± 0.1a,d	.0004
Albumin, mg/dL	3.5–5.2	4.5 ± 0.1	4.5 ± 0.1	4.5 ± 0.1	.99
eGFR, mL/min	≥60	94 ± 6	86 ± 4	79 ± 4	.11
Urine calcium, mg/24 h	35–250	265 ± 37	277 ± 25	222 ± 22	.25
BSAP, U/L	14.2–42.7	40.3 ± 4.6	44.5 ± 3.3	37.4 ± 2.9	.28
CTX, ng/mL	0.142–1.351	0.738 ± 0.08	0.631 ± 0.06	0.604 ± 0.05	.39
FGF-23, RU/mL	43.6 ± 14.3*	90.3 ± 26.2	103.7 ± 19.4	143.6 ± 16.1	.13

Abbreviation: N/A, not applicable. Results represent means ± SEM.

^*Normal mean published value (Ref. 34).

^aP < .001 compared to 25OHD <20 ng/mL.

^bP < .0001 compared to 25OHD <20 ng/mL.

^cP < .05 compared to 25OHD <20 ng/mL.

^dP < .05 compared to 25OHD 20–29 ng/mL.