Table 1.
Baseline Characteristics of Patients Who Received Kisspeptin-54 Trigger
| Characteristics | Kisspeptin-54 Dose (nmol/kg) |
||||
|---|---|---|---|---|---|
| 3.2 | 6.4 | 9.6 | 12.8 | All Doses | |
| N | 5 | 20 | 15 | 20 | 60 |
| Age, y | 30 (28, 31) | 30 (28, 31) | 32 (30, 33) | 31 (28, 34) | 31 (28, 33) |
| Weight, kg | 63 (49, 64) | 60 (54, 66) | 67 (58, 73) | 62 (57, 69) | 63 (56, 68) |
| BMI, kg/m2 | 22 (21, 25) | 22 (20, 27) | 25 (23, 27) | 24 (21, 28) | 24 (21, 27) |
| AFC | 35 (32, 36) | 33 (29, 52) | 38 (27, 50) | 40 (32, 48) | 37 (29, 50) |
| Serum AMH, pmol/L | 35 (29, 50) | 48 (37, 67) | 66 (41, 68) | 53 (43, 68) | 50 (39, 68) |
| Menstrual cycle length, d | 28 (28, 40) | 32 (30, 35) | 35 (30, 41) | 33 (30, 70) | 33 (30, 40) |
| Cause of infertility | |||||
| PCOSa | 2 (40%) | 4 (20%) | 7 (47%) | 10 (50%) | 22 (37%) |
| Tubal defectb | 0 (0%) | 4 (20%) | 0 (0%) | 0 (0%) | 4 (7%) |
| Male factorc | 1 (20%) | 3 (15%) | 3 (20%) | 4 (20%) | 11 (18%) |
| Other | 0 (0%) | 1 (5%) | 0 (0%) | 0 (0%) | 1 (2%) |
| Mixed | 0 (0%) | 1 (5%) | 1 (7%) | 3 (15%) | 5 (8%) |
| Idiopathic | 2 (40%) | 7 (35%) | 4 (27%) | 3 (15%) | 16 (27%) |
| No. of folliclesd | 32 (28, 33) | 30 (26, 35) | 34 (22, 39) | 39 (29, 45) | 34 (26, 40) |
| No. of follicles ≥ 11 mmd | 21 (20, 23) | 19 (15, 26) | 18 (14, 24) | 22 (19, 29) | 21 (16, 25) |
| No. of follicles ≥ 14 mmd | 14 (13, 14) | 12 (9, 16) | 10 (8, 13) | 14 (9, 17) | 13 (9, 16) |
Abbreviation: PCOS, polycystic ovarian syndrome.
Data are expresses as Median (Lower quartile, Upper quartile) for continuous variables and Total (Percentage) for categorical variables.
a
Anovulation due to PCOS.
b
Blocked or removed Fallopian tubes.
c
Infertility due to a problem with male partner's fertility.
d
On final ultrasound scan during controlled ovarian stimulation prior to kisspeptin-54 trigger administration.