Table 3.
Kisspeptin-54 Dose | 3.2 | 6.4 | 9.6 | 12.8 | Total |
---|---|---|---|---|---|
N | 5 | 20 | 15 | 20 | 60 |
≥ 1 mature oocyte retrieved | 4 | 20 | 14 | 19 | 57 |
≥ 1 2PN zygote formeda | 4 | 18 | 13 | 19 | 54 |
Segmentationb | 0 | 1 | 0 | 2 | 3 |
No. of patients with embryo transfer | 4 | 17 | 13 | 17 | 51 |
No. of patients with day 5 transferc | 4 | 15 | 11 | 17 | 47 |
High-quality embryo transferd | 3 | 13 | 9 | 13 | 37 |
Biochemical pregnancy at 11 d | 2 | 11 | 11 | 8 | 32 |
Clinical pregnancy at 6 wk | 1 | 10 | 10 | 6 | 27 |
Miscarriage/still birth | 0 | 1 | 2 | 1 | 4 |
Live birth | 1 | 9 | 8 | 5 | 23 |
Data are presented as the number of patients completing each criterion.
2PN is two pronuclear zygote assessed on day following oocyte retrieval.
Segmentation refers to cryopreservation of all embryos and embryo transfer in a subsequent frozen cycle due to high risk of OHSS.
Embryo transfer on day 5.
Transfer of at least one high-quality embryo. High-quality embryos were blastocyst embryos graded on day 5 as being ≥ 3A or B in quality (30).