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. 2015 Jul 20;100(9):3322–3331. doi: 10.1210/jc.2015-2332

Table 4.

OHSS in High Risk-Women Following Kisspeptin-54 Trigger

Early OHSS Late OHSS
OHSS Symptomatology
    No. of patients screened by OHSS symptoms n = 60 n = 60
    ≥1 symptom potentially consistent with OHSS 9 (15%) 11 (18%)
    No. of patients requiring medical intervention or hospitalization for OHSS 0 0
Sonographical screening
    No. of patients screened with pelvic ultrasound n = 54 n = 51
Left
Right
Left
Right
        Mean ovarian volume (mls) 45 (35) 50 (32) 16 (11) 19 (15)
        Max ovarian diameter (mm) 47 (13) 48 (12) 36 (8) 38 (10)
    No. of patients with maximum ovarian diameter >5 cm 35 (58%) 13 (22%)
    No. of patients with maximum ovarian diameter >8 cm 7 (12%) 9 (15%)
    No. of patients with pleural effusion 0 0
    No. of patients with free fluid in abdomen 0 0
    No. of patients with fluid in POD/adnexa 26 (43%) 8 (13%)
Blood parameters
    No. of patients screened with blood analysis n = 53 n = 50
    No. of patients with hematocrit >45% 0 0
    No. of patients with white cell count >15 × 109/L 0 1
    No. of patients with ALT or AST >2 × ULN 1 (2%) 1 (2%)
    No. of patients with total protein >80 g/L 2 (3%) 4 (7%)
    No. of patient with creatinine >110 μmol/L 0 0
No. of patients with OHSSa
    Normal 57 (95%) 59 (98%)
    Mild 3 (5%) 1 (2%)
    Moderate 0 0
    Severe 0 0
    Critical 0 0

Abbreviations: POD, Pouch of douglas; ALT, Alanine transaminase; ULN, Upper Limit of Normal.

a

Diagnosis of OHSS was performed by two experienced IVF physicians independent of the study team provided with blinded data according to the criteria (16) with updated categorization of severe and critical OHSS (17).