Table 3.
Linear Regression Models for Infant Preprandial Insulin and HOMA-IR
| Effect | Insulin Model |
HOMA-IR Model |
||
|---|---|---|---|---|
| Coefficient | P Value | Coefficient | P Value | |
| Infant HIV/ARV exposure status | ||||
| HIV/ARV unexposed | 0 | 0 | ||
| HIV/ARV exposed to postnatal NVP | −0.070 | .022 | −0.045 | .060 |
| HIV/ARV exposed to postnatal AZT | −0.116 | .012 | −0.080 | .022 |
| Maternal age, per year | −0.001 | .941 | −0.001 | .776 |
| Highest level of education | ||||
| Secondary school or lower | −0.027 | .325 | −0.013 | .520 |
| High school or higher | 0 | 0 | ||
| Maternal gestational diabetes status | ||||
| Gestational diabetes | 0.065 | .261 | 0.057 | .186 |
| No gestational diabetes | 0 | 0 | ||
| Infant gender | ||||
| Female | −0.010 | .709 | −0.011 | .582 |
| Male | 0 | 0 | ||
| Low birth weight (<2500 g) | −0.039 | .595 | −0.011 | .849 |
| Preterm birth (<37 wk) | −0.001 | .982 | 0.006 | .832 |
| Infant WLZ at 6-week visit | 0.003 | .623 | 0.001 | .873 |
| PC1, long-chain ACs, C0, and C5 | 0.003 | .831 | 0.005 | .642 |
| PC2, 3-hydroxy long-chain ACs | −0.009 | .535 | −0.005 | .673 |
| PC3, short-chain and BCAA-related ACs | 0.044 | .001 | 0.037 | .002 |
| PC4, unsaturated medium- and long-chain ACs | −0.029 | .101 | −0.025 | .061 |
| PC5, BCAAs | 0.034 | .012 | 0.023 | .024 |
| PC6, C6-DC and C12 ACs | 0.010 | .496 | 0.006 | .568 |
| PC7, Medium-chain ACs and C14:1 | 0.001 | .991 | −0.001 | .949 |
| HIV/ARV exposed to postnatal NVP PC4 | 0.095 | .002 | 0.078 | .001 |
| HIV/ARV exposed to postnatal AZT PC4 | 0.166 | .001 | 0.118 | .001 |