Table 1. Panels of classifiers.
| Symbol | Full name | AUC | Sensitivity(%) | Specificity(%) | PPV | NPV |
|---|---|---|---|---|---|---|
| HC vs Grade II | ||||||
| SNX1 | sorting nexin 1 | 0.9 | 88 | 87 | 0.88 | 0.87 |
| MYLK | myosin light chain kinase | |||||
| VDAC1 | voltage-dependent anion channel 1 | |||||
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) | |||||
| CCDC32 | coiled-coil domain containing 32 | |||||
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | |||||
| CD44 | CD44 molecule (Indian blood group) | |||||
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | |||||
| PQBP1 | polyglutamine binding protein 1 | |||||
| EXOSC7 | exosome component 7 | |||||
| HC vs Grade III | ||||||
| C14orf80 | chromosome 14 open reading frame 80 | 1 | 89 | 100 | 1 | 0.88 |
| GCK | glucokinase (hexokinase 4) | |||||
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 | |||||
| LYPLAL1 | lysophospholipase-like 1 | |||||
| MAGEA4 | melanoma antigen family A, 4, | |||||
| MLX | MLX, MAX dimerization protein | |||||
| RTN4 | reticulon 4 | |||||
| SNX1 | sorting nexin 1 | |||||
| TEX264 | testis expressed 264 | |||||
| ARHGAP17 | Rho GTPase activating protein 17 | |||||
| HC vs Grade IV | ||||||
| SNX1 | sorting nexin 1 | 0.975 | 94 | 73 | 0.89 | 0.85 |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) | |||||
| C11orf74 | chromosome 11 open reading frame 74 | |||||
| C17orf57 | EF-hand calcium binding domain 13 | |||||
| CIB1 | calcium and integrin binding 1 (calmyrin) | |||||
| RCSD1 | RCSD domain containing 1 | |||||
| CDH26 | cadherin 26 | |||||
| PQBP1 | polyglutamine binding protein 1 | |||||
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | |||||
| ZHX3 | zinc fingers and homeoboxes 3 | |||||
| SVZp vs SVZn | ||||||
| NEDD9 | neural precursor cell expressed | 0.975 | 77 | 95 | 0.91 | 0.87 |
| PGM2 | phosphoglucomutase 2 | |||||
| DR1 | down-regulator of transcription 1 | |||||
| FAM120B | family with sequence similarity 120B | |||||
| TMOD4 | tropomodulin 4 (muscle) | |||||
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | |||||
| GPBP1 | GC-rich promoter binding protein 1 | |||||
| GMEB1 | glucocorticoid modulatory element binding protein 1 eukaryotic translation elongation factor 1 alpha 1 | |||||
| EEF1A1 | Eukaryotic Translation Elongation Factor 1 Alpha | |||||
| LOC339685 | LOC339685 | |||||
This table shows the sensitivities, specificities and the corresponding AUC values for various comparisons (AUC: Area under curve; PPV: positive predictive value; NPV: negative predictive value).