Table 4.

Evaluation of similarity/overlap between the signatures of different cancer types using the frequency-based measure

	GBM			LAML			LUSC			SKCM
	mRNA	methy	CNA	mRNA	methy	CNA	mRNA	methy	CNA	mRNA	methy	CNA
BRCA
Raw	12	94	91	12	67	144	4	36	26	22	93	78
Jaccard	0.032	0.490	0.094	0.047	0.396	0.129	0.022	0.277	0.060	0.057	0.492	0.113
Overlap score	3.097	23.596	28.362	5.373	14.584	44.605	0.746	9.269	8.459	6.347	26.028	23.814
GBM
Raw				31	141	412	10	72	103	49	187	237
Jaccard				0.074	0.731	0.286	0.028	0.375	0.109	0.090	0.969	0.211
Overlap score				8.878	38.684	97.607	3.878	18.402	30.281	13.421	46.849	61.942
LAML
Raw							5	49	135	27	139	275
Jaccard							0.021	0.297	0.122	0.061	0.728	0.215
Overlap score							1.362	13.939	38.494	8.137	34.630	79.060
LUSC
Raw										10	69	61
Jaccard										0.026	0.361	0.088
Overlap score										3.004	17.880	19.716

mRNA, methy and CNA correspond to gene expression, methylation and CNA, respectively.