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. 2015 Aug 15;63(35):7862–7872. doi: 10.1021/acs.jafc.5b02697

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Copyright © 2015 American Chemical Society

This is an open access article published under a Creative Commons Attribution (CC-BY) License, which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.

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Overlaid extracted ion chromatograms (EICs) based on MetExtract data processing output showing the biotransformation products of a sample treated with a mixture of ¹²C/¹³C-HT-2 toxin (red trace) and one treated with a mixture of ¹²C/¹³C T-2 toxin (blue trace). EICs of nonlabeled metabolites are displayed with positive intensity values; those of the corresponding labeled metabolites are displayed as negative intensities. Perfect coelution, similar peak shape, and ¹²C/¹³C-intensities of EIC peaks verify the detected ions are truly tracer-derived metabolites.