Table 1.
Status at 10-year follow – up | ||||
---|---|---|---|---|
Baseline | CVD event free (n = 1703) | CVD events (n = 317) | p | |
Age, yrs | 45 ± 14 | 43 ± 13 | 58 ± 13 | <0.001 |
Male gender, % | 50 % | 48 % | 63 % | <0.001 |
Years of school | 12 ± 4 | 13 ± 4 | 10 ± 4 | <0.001 |
Smoking at baseline or before, % | 43 % | 55 % | 57 % | 0.462 |
Physical activity, % | 41 % | 41 % | 41 % | 0.999 |
MedDietScore (0–55) | 26 ± 7 | 26 ± 6 | 23 ± 7 | <0.001 |
Hypertension, % | 30 % | 28 % | 51 % | <0.001 |
Hypercholesterolemia, % | 39 % | 40 % | 57 % | <0.001 |
Use of lipid-lowering meds, % | 25 % | 38 % | 21 % | <0.001 |
Total cholesterol, mmol/L | 4.99 ± 1.09 | 4.99 ± 1.06 | 5.33 ± 1.09 | <0.001 |
HDL-cholesterol, mmol/L | 1.24 ± 0.39 | 1.27 ± 0.39 | 1.16 ± 0.31 | <0.001 |
LDL-cholesterol, mmol/L | 3.15 ± 0.96 | 3.13 ± 0.96 | 3.39 ± 1.03 | <0.001 |
Apolipoprotein AI, mg/dL | 154 ± 27 | 156 ± 27 | 150 ± 24 | 0.001 |
Apolipoprotein B, mg/dL | 108 ± 38 | 106 ± 42 | 109 ± 29 | <0.001 |
Triglycerides, mmol/L** | 1.13 ± 0.42 | 1.08 ± 0.41 | 1.48 ± 0.51 | <0.001 |
Lipoprotein-a, mg/dL** | 11 ± 9.5 | 11 ± 9.5 | 13 ± 11 | 0.052 |
Diabetes, % | 7 % | 5 % | 22 % | <0.001 |
Obesity, % | 18 % | 17 % | 28 % | <0.001 |
Family history of CVD, % | 28 % | 28 % | 32 % | 0.297 |
*p-values for the comparisons between CVD event and event-free group derived using the t-test for age, total, HDL-cholesterol and MedDietScore or Mann–Whitney non-parametric test (**) for years of school and the rest lipids, while for the comparisons of categorical variables using the chi-square test