Table 3.
Classification indices from survival models that evaluated the association of blood lipids and lipoproteins on 10-year CVD incidence, among the ATTICA study participants (n = 2020)
| Independent predictor | Adj. R2 | Harrell’s C | cNRI |
|---|---|---|---|
| Model 1: Total cholesterol (per 1 mg/dL*) | 17.4 % | 0.205 | 10.4 % |
| Model 2: HDL cholesterol (per 1 mg/dL) | 17.8 % | 0.521 | 12.6 % |
| Model 3: LDL cholesterol (per 1 mg/dL) | 17.6 % | 0.739 | 11.1 % |
| Model 4: non-HDL cholesterol (per 1 mg/dL) | 18 % | 0.383 | 21.2 % |
| Model 5: Triglycerides (per 1 mg/dL) | 17.3 % | 0.707 | 5.0 % |
| Model 5: Lipoprotein-a (per 1 mg/dL) | 17.6 % | 0.562 | 6.7 % |
| Model 6: Apolipoprotein-A1 (per 1 mg/dL) | 17.9 % | 0.271 | 3.4 % |
| Model 7: Apolipoprotein-B (per 1 mg/dL) | 17.7 % | 0.277 | 19.7 % |
| Model 8: Total/HDL-cholesterol ratio (per 1 unit) | 18.5 % | 0.901 | 21 % |
| Model 9: Apolipoprotein-B/-A1 ratio (per 1 unit) | 17.7 % | 0.417 | 26.1 % |
| Model 10: Triglycerides/HDL-cholesterol ratio (per 1 unit) | 18.2 % | 0.616 | 14.8 % |
Model refers to the ones presented in Table 2
cNRI Continuous Net Reclassification Index
*1 mg/dL corresponds to 0.0259 mmol/L for Total cholesterol, HDL cholesterol, LDL cholesterol, non-HDL cholesterol and to 0.0115 mmol/L for Triglycerides