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Schematic diagram of the regulatory network of mRNA translation. 4E-BPs (green), eIF4G (light blue), 4E-T (brown), and CYFIP1 (peach) compete for the canonical binding site of eIF4E (blue). Translation of mRNA (gray) is inhibited by CYFIP1, 4E-BP and 4E-T binding. eIF4G is a translational activator.
