Table II.
Average Hydrophobic, Hydrophilic, and Total Solvent-Accessible Surface Area of Wild Type (WT) and Mutants of the Various Dimers in (Å2) as Calculated Using Last 50 ns of the Trajectories
| System | SASAHPHOB | ΔSASAHPHOB | SASAHPHIL | ΔSASAHPHIL | SASA | ΔSASA |
|---|---|---|---|---|---|---|
| WT | 3475 (80) | 7502 (83) | 10977 (146) | |||
| R61N | 3399 (83) | −76 | 7575 (126) | 73 | 10974 (153) | −3 |
| G68D | 3468 (89) | −7 | 7628 (129) | 126 | 11096 (157) | 119 |
| D82I | 3449 (84) | −26 | 7604 (122) | 102 | 11053 (144) | 76 |
| A84T | 3453 (86) | −22 | 7554 (124) | 52 | 11007 (149) | 30 |
Standard deviations are calculated over three independent runs and shown in parentheses.
HPHOB = hydrophobic; HPHIL = hydrophilic; ΔSASA = SASAmutant − SASAWT.