Table IV.
System | Native | Difference | Amyloid | Difference | ΔΔG╪ |
---|---|---|---|---|---|
WT | −1964 (31) | −1943 (31) | |||
R61N | −1842 (30) | 122 | −1827 (31) | 116 | −6 |
G68D | −2015 (31) | −51 | −1999 (30) | −56 | −5 |
D82I | −1884 (30) | 80 | −1848 (31) | 95 | 15 |
A84T | −1988 (31) | −24 | −1979 (31) | −36 | −8 |
Data are in (kcal mol−1). Standard deviations are calculated over three independent runs and shown in parentheses.
ΔΔG╪ = Difference (amyloid) – Difference (native).