Figure 3. Hepatic long chain acyl CoA and free fatty acid content.
(a) Livers from FGF21-KO mice on MCD for 8 weeks showed reduced levels of all the species of long chain acyl CoAs measured. (b) Reduced total LCCoA in FGF21-KO. (c) Compared to WT mice, FGF21KO mice have higher hepatic levels of free fatty acids. Data are expressed as mean ± SEM, with N = 6 per group. (*, P < 0.05; **, P < 0.01; *** P< 0.001).