Table 3.

Comparisons of serum magnesium levels in controls, short-term PPI group, and long-term PPI group

	Control	Short-term PPI use (< 12 mo)	Long-term PPI use (≥ 12 mo)	P⁎	P†
Baseline (mg/dL)	2.03±0.18	2.02±0.18	2.04±0.19	0.851
Follow-up (mg/dL)	2.07±0.21	2.05±0.20	2.06±0.17	0.347
Change (mg/dL)	0.04±0.23	0.02±0.23	0.03±0.22	0.540	0.213

Values indicate the mean ± SD.

ANCOVA, analysis of covariance; ANOVA, analysis of variance; GFR, glomerular filtration rate; K, potassium; Mg, magnesium; PPI, proton pump inhibitor.

^⁎P value by ANOVA

^†P value by ANCOVA adjusting for age, sex, baseline GFR, baseline Mg, use of diuretics, and baseline K