Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Effect of MAPK inhibitors on aldosterone-induced EMT. ERK 1/2 inhibitor (PD98059, 10μM) and p38 inhibitor (SB203589, 10μM) alleviated the decrease of E-cadherin and acquisition of α-SMA in aldosterone-exposed cells at 48 hours. Representative western blotting and its quantitation graphs are shown (n=6). ⁎P<0.05 versus others. EMT, epithelial-to-mesenchymal transition; ERK, extracellular signal-regulated kinase; MAPK, mitogen-activated protein kinase; SMA, smooth muscle actin.
