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. 2015 Sep 15;10(9):e0137478. doi: 10.1371/journal.pone.0137478

Table 2. Distribution of subjects who were candidates for lipid-lowering drug therapy for primary prevention (age 20–79 years).

Total Men Women
(n = 5,837) (n = 4,209) (n = 1,628)
N (%) N (%) N (%)
2013 ACC/AHA guideline
  LDL-C ≥ 190 mg/dl 90 (1.5) 46 (1.1) 44 (2.7)
  Diabetes & 40–75 & LDL 70–189 mg/dL 663 (11.4) 558 (13.3) 105 (6.4)
  No Diabetes & 40–75 & LDL 70–189 mg/dL& ASCVD≥ 7.5% 1210 (20.7) 1134 (26.9) 76 (4.7)
Total candidates 1963 (33.6) 1738 (41.3) 225 (13.8)
2004 ATP III guideline
  CHD risk equivalents * & LDL-C≥ 100 mg/dl 597 (10.2) 510 (12.1) 87 (5.3)
  No Diabetes & CHD risk factor ≥ 2
    CHD risk 10–20% & LDL-C ≥ 130 mg/dl 263 (4.5) 258 (6.1) 5 (0.3)
    CHD risk <10% & LDL-C ≥ 160 mg/dl 49 (0.8) 35 (0.8) 14 (0.9)
  No CHD & no Diabetes & CHD risk factor 0–1
    LDL-C ≥ 190 mg/dl 46 (0.8) 15 (0.4) 31 (1.9)
Total candidates 955 (16.4) 818 (19.4) 137 (8.4)
Subjects eligible for statins by 2013 ACC/AHA guideline only 1110 (19.0) 1013 (24.1) 97 (6.0)
Subjects eligible for statins by 2004 ATP III guideline only 102 (1.7) 93 (2.2) 9 (0.6)
Subjects eligible for statins by both guidelines 853 (14.6) 725 (17.2) 128 (7.9)

ACC/AHA, American College of Cardiology / American Heart Association; LDL-C, low-density lipoprotein cholesterol; ASCVD, atherosclerotic cardiovascular disease; ATP, Adult Treatment Panel; CHD, coronary heart disease.

*Diabetes or CHD risk factor ≥ 2 & CHD risk >20%.