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. 2015 Sep 15;16(1):190. doi: 10.1186/s13059-015-0722-1

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© Wang et al. 2015

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — CPAG software. Workflow depicting how CPAG software detects trait similarity and provides a means for visualizing and mining similarity for hypothesis generation. User-generated lists of SNPs are used as input to make comparisons with the entire NHGRI GWAS Catalog based on SNPs, LD-corrected SNPs, or genes. In addition to a text read-out of similarity that includes a description of the SNPs, strength and significance of similarity, and GSEA of pathways underlying the similarity, results can be visualized by hierarchical clustering or by networks. CPAG software can be downloaded at [36]