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. 2015 Sep 15;10(9):e0136425. doi: 10.1371/journal.pone.0136425

Fig 11. Painful effect induced by hNGF WT or mutants.

Fig 11

Pooled data of the mechanical allodynic response (A) and the thermal (hot) hyperalgesic response (B) evoked by intraplantar (i.pl.) injection (20 μl) of hNGF WT, hNGF R100E, hNGF P61S, hNGF P61S R100E or their vehicle (Veh, isotonic saline), measured 5 hours post-treatment. Data are mean ± sem of at least n = 4 mice per group; *P<0.05 vs. Veh or hNGF WT 0.1 μg or hNGF P61S 0.1 μg; #P<0.05 vs. hNGF WT 1 μg or hNGF P61S 0.1 μg; §P<0.05 vs. hNGF WT 10 μg or hNGF P61S 10 μg. One-way ANOVA followed by Bonferroni post-test.