Table 2. Inflection points extrapolated by the chemical denaturation profiles of human NGF and proNGF Wild Type and mutants.
hNGF WT | hNGF P61S | hNGF R100E | hNGF P61S R100E | |
inflection point (M) | 3.0 | 2.8 | 3.2 | 3.0 |
hproNGF WT | hproNGF P61S | hproNGF R100E | hproNGF P61S R100E | |
inflection point 1 (M) | 1.5 | 1.5 | 1.0 | 1.0 |
inflection point 2 (M) | 4 | 3.8 | 4.2 | 3.2 |