Table 3.
Anthropometric, clinical and biochemical features of patients with type 2 diabetes according to tertiles of CV-HbA1c
| CV-HbA1c tertiles | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Low | Median | High | ||||||||
| (1.17-3.64) | (3.64-6.50) | (6.50-28.65) | p values | |||||||
| Smokers (n, %) | 10 | , | 18.2 | 22 | , | 39.3 | 25 | , | 44.6 | 0.008 |
| Age (years) | 63.6 | ± | 9.6 | 62.3 | ± | 9.4 | 61.2 | ± | 11.3 | 0.453 |
| BMI (kg/m2) | 24.0 | ± | 3.9 | 24.1 | ± | 3.0 | 24.6 | ± | 4.0 | 0.638 |
| Waist circumference (cm) | 87.2 | ± | 9.4 | 86.6 | ± | 8.7 | 87.0 | ± | 11.5 | 0.959 |
| Duration of diabetes (years) | 9.2 | ± | 7.7 | 10.6 | ± | 6.7 | 9.8 | ± | 7.5 | 0.622 |
| Treatment of | ||||||||||
| diabetes; diet/OHA/insulin (%) | 43/50/7 | 32/45/23 | 20/ 57/ 23 | 0.026 | ||||||
| hypertension; CCB/RASi/diuretics (%) | 36/39/5 | 30/41/4 | 38/ 45/ 5 | 0.424 | ||||||
| HbA1c (%) | 6.6 | ± | 0.6 | 7.1 | ± | 0.7 | 7.4 | ± | 1.0 | <0.001 |
| Fasting PG (mg/dL) | 114 | ± | 14 | 129 | ± | 24 | 133 | ± | 23 | <0.001 |
| Post-breakfast PG (mg/dL) | 135 | ± | 40 | 160 | ± | 49 | 169 | ± | 51 | 0.001 |
| CV-HbA1c (%) | 2.5 | ± | 0.7 | 4.9 | ± | 0.9 | 13.6 | ± | 7.3 | <0.001 |
| CV-Fasting PG (%) | 8.8 | ± | 3.9 | 14.1 | ± | 9.7 | 19.5 | ± | 9.6 | <0.001 |
| CV-Post-breakfast PG (%) | 18 | ± | 10 | 23 | ± | 11 | 25 | ± | 11 | 0.007 |
| Total cholesterol (mg/dL) | 188 | ± | 19 | 189 | ± | 18 | 187 | ± | 25 | 0.890 |
| LDL cholesterol (mg/dL) | 108 | ± | 17 | 111 | ± | 23 | 114 | ± | 25 | 0.288 |
| HDL cholesterol (mg/dL) | 60 | ± | 15 | 57 | ± | 17 | 50 | ± | 12 | 0.001 |
| Fasting TG (mg/dL) | 102 | ± | 43 | 112 | ± | 49 | 130 | ± | 58 | 0.017 |
| Post-breakfast TG (mg/dL) | 131 | ± | 59 | 144 | ± | 65 | 137 | ± | 65 | 0.047 |
| Serum creatinine (mg/dL) | 0.73 | ± | 0.15 | 0.73 | ± | 0.15 | 0.80 | ± | 0.25 | 0.072 |
| eGFR (mL/min/1.73m2) | 74 | ± | 12 | 76 | ± | 15 | 77 | ± | 21 | 0.641 |
| ⊿eGFR (mL/min/1.73m2/year) | −0.69 | ± | 2.77 | −0.63 | ± | 2.29 | −2.19 | ± | 3.68 | 0.008 |
| Uric acid (mg/dL) | 5.3 | ± | 1.5 | 5.0 | ± | 1.4 | 5.2 | ± | 1.1 | 0.495 |
| Systolic BP (mmHg) | 128 | ± | 12 | 129 | ± | 11 | 128 | ± | 13 | 0.905 |
| CV-Systolic BP (%) | 8.2 | ± | 2.3 | 7.6 | ± | 2.1 | 8.3 | ± | 2.2 | 0.254 |
| Diastolic BP (mmHg) | 72 | ± | 6 | 72 | ± | 7 | 72 | ± | 7 | 0.787 |
| Urinary ACR (mg/g) | 21 | ± | 24 | 69 | ± | 152 | 162 | ± | 532 | 0.066 |
| log ACR | 1.1 | ± | 0.5 | 1.4 | ± | 0.6 | 1.4 | ± | 0.7 | 0.012 |
Mean ± SD or n, %. Abbreviations are the same as in Table 1