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. 2015 Sep 14;14:69. doi: 10.1186/s40200-015-0201-y

Table 3.

Anthropometric, clinical and biochemical features of patients with type 2 diabetes according to tertiles of CV-HbA1c

CV-HbA1c tertiles
Low Median High
(1.17-3.64) (3.64-6.50) (6.50-28.65) p values
Smokers (n, %) 10 , 18.2 22 , 39.3 25 , 44.6 0.008
Age (years) 63.6 ± 9.6 62.3 ± 9.4 61.2 ± 11.3 0.453
BMI (kg/m2) 24.0 ± 3.9 24.1 ± 3.0 24.6 ± 4.0 0.638
Waist circumference (cm) 87.2 ± 9.4 86.6 ± 8.7 87.0 ± 11.5 0.959
Duration of diabetes (years) 9.2 ± 7.7 10.6 ± 6.7 9.8 ± 7.5 0.622
Treatment of
diabetes; diet/OHA/insulin (%) 43/50/7 32/45/23 20/ 57/ 23 0.026
hypertension; CCB/RASi/diuretics (%) 36/39/5 30/41/4 38/ 45/ 5 0.424
HbA1c (%) 6.6 ± 0.6 7.1 ± 0.7 7.4 ± 1.0 <0.001
Fasting PG (mg/dL) 114 ± 14 129 ± 24 133 ± 23 <0.001
Post-breakfast PG (mg/dL) 135 ± 40 160 ± 49 169 ± 51 0.001
CV-HbA1c (%) 2.5 ± 0.7 4.9 ± 0.9 13.6 ± 7.3 <0.001
CV-Fasting PG (%) 8.8 ± 3.9 14.1 ± 9.7 19.5 ± 9.6 <0.001
CV-Post-breakfast PG (%) 18 ± 10 23 ± 11 25 ± 11 0.007
Total cholesterol (mg/dL) 188 ± 19 189 ± 18 187 ± 25 0.890
LDL cholesterol (mg/dL) 108 ± 17 111 ± 23 114 ± 25 0.288
HDL cholesterol (mg/dL) 60 ± 15 57 ± 17 50 ± 12 0.001
Fasting TG (mg/dL) 102 ± 43 112 ± 49 130 ± 58 0.017
Post-breakfast TG (mg/dL) 131 ± 59 144 ± 65 137 ± 65 0.047
Serum creatinine (mg/dL) 0.73 ± 0.15 0.73 ± 0.15 0.80 ± 0.25 0.072
eGFR (mL/min/1.73m2) 74 ± 12 76 ± 15 77 ± 21 0.641
⊿eGFR (mL/min/1.73m2/year) −0.69 ± 2.77 −0.63 ± 2.29 −2.19 ± 3.68 0.008
Uric acid (mg/dL) 5.3 ± 1.5 5.0 ± 1.4 5.2 ± 1.1 0.495
Systolic BP (mmHg) 128 ± 12 129 ± 11 128 ± 13 0.905
CV-Systolic BP (%) 8.2 ± 2.3 7.6 ± 2.1 8.3 ± 2.2 0.254
Diastolic BP (mmHg) 72 ± 6 72 ± 7 72 ± 7 0.787
Urinary ACR (mg/g) 21 ± 24 69 ± 152 162 ± 532 0.066
log ACR 1.1 ± 0.5 1.4 ± 0.6 1.4 ± 0.7 0.012

Mean ± SD or n, %. Abbreviations are the same as in Table 1