Table 4. Correlation analysis of clinical data and brain MRI visual rating scores in AD and MCI patients.
| Age | Education years | MMSE | CDR-SB | NPI-agitation /aggression | NPI-mood | |
|---|---|---|---|---|---|---|
| MTA | 0.31* | 0.19 | -0.30* | 0.34* | 0.18 | 0.09 |
| PA | 0.40* | 0.06 | -0.09 | 0.15 | 0.26* | 0.16 |
| FWMH | 0.27* | 0.04 | -0.14 | 0.10 | 0.14 | 0.13 |
| POWMH | 0.32* | 0.07 | -0.00 | 0.03 | 0.17 | 0.19 |
| TWMH | 0.19 | 0.16 | -0.02 | 0.07 | 0.22* | 0.23 |
| TOWMH | 0.28* | 0.08 | -0.06 | 0.08 | 0.20 | 0.22* |
Values are Pearson correlation coefficients.
MRI, magnetic resonance imaging; AD, Alzheimer’s disease; MCI, mild cognitive impairment; MTA, medial temporal atrophy; PA, posterior atrophy; FWMH, frontal white matter hyperintensity; POWMH, parieto-occipital white matter hyperintensity; TWMH, temporal white matter hyperintensity; TOWMH, total white matter hyperintensity; MMSE, Mini-Mental State Examination; NPI, Neuropsychiatric Inventory; CDR-SB, clinical dementia rating sum of boxes.
*p < 0.01.