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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: J Invest Dermatol. 2015 May 8;135(10):2519–2529. doi: 10.1038/jid.2015.182

Figure 3. Wound closure and re-epithelialization.

Figure 3

(a) Wounds on day 14: (i) representative wound images; (ii) percentage closed wounds gap and (iii) open wound area. D= dressing-only treated wounds; H= hydrogel treated wounds; D-R= dressing retreated wounds; H-R= hydrogel retreated wounds. N=7 for D and H and N=3 for D-R and H-R. (b, c) Wounds on day 14: (i) representative wound images and (ii) immunohistochemistry for K14 (upper panel; arrows indicate open wound) and masson trichrome stain (lower panel). High magnifications of the boxed areas are shown on the right.; (c) Wounds on day 14: (d) Quantification of (i) rete percentage and (ii) rete density of day 14-treated wound. N=3. Scale bars are 1cm in ai and bi; 1mm in aii, bii and 0.5mm in high magnification inserts. Significance levels were set at *p<0.05, **p<0.01, and ***p<0.001.