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. Author manuscript; available in PMC: 2016 Jun 16.
Published in final edited form as: Immunity. 2015 Jun 9;42(6):1159–1170. doi: 10.1016/j.immuni.2015.05.012

Fig. 5. Strong TCR stimulation induce naïve Th cells to express Tfh molecules.

Fig. 5

(A) Bcl-6 expression by naïve Th cells transfected with the indicated siRNA and cultured for 3 days with anti-CD3 and CD28 ± sOX40L. Gated to FSChiSSChi activated cells. Mean ± s.e.m., n=3.

(B) Expression of the indicated markers by naïve Th cells activated for 4 days with the indicated number of anti-CD3 and anti-CD28-coated beads. Gated to FSChiSSChi activated cells. A representative result out of 3 independent experiments is shown.