Table 1.
Geometric means (95% CI) of creatinine-corrected phenol biomarker concentrations in urine (µg/g creatinine) collected at baseline in relation to covariates.
| Covariate | N | Benzophenone-3 | Enterolactone | 2,5-Dichlorophenol | Triclosan | |
|---|---|---|---|---|---|---|
| Age at baseline urine, years | 6.0–6.9 | 307 | 44.9 (35.4–56.8)* | 408 ( 357, 467)* | 22.2 (17.8, 27.6)* | 17.4 (14.6, 20.8) |
| 7.0–7.9 | 609 | 43.1 (36.5–51.0) | 516 ( 468, 568) | 11.3 (9.70, 13.2) | 17.6 (15.5, 20.1) | |
| >=8.0 | 254 | 21.5 (16.6–27.9) | 374 ( 322, 434) | 29.4 (23.1, 37.3) | 20.1 (16.5, 24.5) | |
| Race/ethnicity | Asian | 56 | 104 (62.1, 176)* | 484 ( 355, 660)* | 5.96 (3.81, 9.31)* | 14.1 (9.29, 21.5) |
| Black | 366 | 17.0 (13.8, 20.8) | 446 ( 394, 505) | 34.0 (28.6, 40.5) | 18.8 (16.0, 22.2) | |
| Hispanic | 360 | 25.7 (20.9, 31.5) | 349 ( 309, 395) | 40.0 (33.5, 47.7) | 16.5 (14.0, 19.5) | |
| White | 388 | 97.1 (79.7, 118) | 575 ( 511, 647) | 4.32 (3.64, 5.12) | 19.7 (16.8, 23.2) | |
| BMI% at last B1 visit | <50th Percentile | 390 | 47.4 (38.4, 58.6)* | 564 ( 501, 635)* | 13.1 (10.8, 15.9)* | 19.8 (16.9, 23.2) |
| 50–85th Percentile | 376 | 35.2 (28.4, 43.6) | 477 ( 423, 539) | 15.4 (12.6, 18.8) | 17.4 (14.7, 20.4) | |
| >=85th Percentile | 403 | 31.7 (25.8, 39.0) | 345 ( 307, 388) | 22.5 (18.6, 27.3) | 17.4 (14.8, 20.3) | |
| BMI% at last PH1 visit | <50th Percentile | 387 | 49.8 (40.3, 61.5)* | 566 ( 503, 637)* | 12.3 (10.1, 15.0)* | 19.5 (16.6, 22.9) |
| 50–85th Percentile | 374 | 33.3 (26.9, 41.3) | 483 ( 428, 546) | 16.2 (13.3, 19.8) | 17.3 (14.7, 20.3) | |
| >=85th Percentile | 403 | 31.7 (25.8, 39.0) | 339 ( 301, 381) | 22.6 (18.7, 27.5) | 17.7 (15.1, 20.7) | |
| Caregiver education | <= HS | 348 | 20.1 (16.1, 25.1)* | 344 ( 303, 390)* | 43.1 (35.3, 52.6)* | 17.8 (15.0, 21.0) |
| > HS | 794 | 50.2 (43.4, 58.1) | 512 ( 471, 556) | 10.8 (9.51, 12.4) | 18.0 (16.1, 20.2) | |
| Site | California | 434 | 106 (88.5, 128)* | 627 ( 561, 701)* | 5.09 (4.39, 5.89)* | 13.2 (11.4, 15.3)* |
| New York | 405 | 14.8 (12.2, 17.9) | 336 ( 300, 377) | 86.6 (74.4, 101) | 17.1 (14.7, 19.9) | |
| Ohio | 331 | 29.8 (24.1, 36.8) | 426 ( 375, 484) | 10.4 (8.77, 12.3) | 29.0 (24.5, 34.4) | |
| Season at urine | Fall | 229 | 24.8 (19.4, 31.7)* | 503 ( 428, 592) | 26.0 (20.1, 33.5) | 16.1 (13.0, 20.0) |
| Spring | 388 | 24.4 (20.2, 29.4) | 440 ( 390, 496) | 13.5 (11.1, 16.4) | 19.4 (16.5, 22.8) | |
| Summer | 322 | 175 ( 142, 215) | 429 ( 376, 489) | 11.8 (9.53, 14.6) | 17.3 (14.5, 20.6) | |
| Winter | 228 | 13.4 (10.5, 17.2) | 459 ( 392, 538) | 24.8 (19.2, 32.0) | 19.0 (15.4, 23.4) | |
| ALL | 1170 | 37.5 (33.2, 42.3) | 452 ( 422, 484) | 16.6 (14.8, 18.6) | 18.1 (16.5, 19.8) | |
Asterisks after the first category indicates that the biomarker varies by that characteristic, p<.05 for unadjusted geometric means by ANOVA. There were 1170 girls with at least one biomarker and creatinine. There were 1170 observations with at least one biomarker and creatinine. Not all girls had all biomarkers, as detailed in Suppl Table 1.