Table 2. Creatinine-adjusted urinary phthalate metabolite concentrations in the Shanghai Men's and Shanghai Women's Health.
| Phthalate Metabolite (μg/g creatinine)a | Sample 1b | Sample 2 | Sample 3 | ||||||
|---|---|---|---|---|---|---|---|---|---|
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| % >LODc | GM | (5th, 95th percentile) | % >LOD | GM | (5th, 95th percentile) | % >LOD | GM | (5th, 95th percentile) | |
| Males | (N=48) | (N=50) | (N=50) | ||||||
| MBP | 100 | 105 | (34.1, 289) | 100 | 66.1 | (30.2, 173) | 100 | 65.6 | (24.8, 208) |
| MiBP | 100 | 56.6 | (23.2, 139) | 100 | 45.6 | (18.3, 114) | 100 | 50.5 | (19.3, 143) |
| MEP | 100 | 9.98 | (1.93, 163) | 100 | 13.2 | (2.14, 433) | 100 | 10.6 | (2.75, 49.0) |
| MBzP | 65 | 0.566 | (<LOD, 3.49) | 70 | 0.450 | (<LOD, 4.78) | 60 | 0.407 | (<LOD, 4.63) |
| MCNP | 33 | d | (<LOD, 0.893) | 46 | d | (<LOD, 0.891) | 24 | d | (<LOD, 0.481) |
| MCOP | 75 | 0.444 | (<LOD, 4.37) | 88 | 0.675 | (<LOD, 3.12) | 88 | 0.715 | (0.220, 14.8) |
| MCPP | 90 | 0.952 | (<LOD, 3.17) | 90 | 0.705 | (<LOD, 2.56) | 90 | 0.617 | (0.213, 2.09) |
| MECPP | 100 | 29.3 | (12.0, 95.4) | 100 | 26.0 | (10.9, 123) | 100 | 30.8 | (12.8, 168) |
| MEHHP | 100 | 21.0 | (5.83, 110) | 100 | 18.8 | (7.01, 88.6) | 100 | 21.3 | (8.73, 99.9) |
| MEHP | 92 | 4.24 | (0.779, 33.2) | 90 | 3.57 | (0.663, 19.0) | 96 | 3.40 | (1.08, 13.3) |
| MEOHP | 100 | 12.4 | (3.67, 54.9) | 100 | 11.2 | (4.37, 53.8) | 100 | 13.0 | (5.08, 68.6) |
| ΣLMWPe | 8.91 | (2.72, 29.8) | 7.40 | (3.07, 27.0) | 6.33 | (2.56, 14.5) | |||
| ΣHMWP e | 2.51 | (0.884, 10.0) | 2.15 | (0.818, 9.41) | 2.45 | (0.976, 11.7) | |||
| ΣDEHPe | 2.30 | (0.859, 10.0) | 2.05 | (0.801, 9.36) | 2.34 | (0.942, 11.7) | |||
| ΣDBPe | 7.58 | (2.58, 17.1) | 5.25 | (2.37, 10.7) | 5.46 | (2.16, 14.0) | |||
| Females | (N=49) | (N=49) | (N=50) | ||||||
| MBP | 100 | 151 | (48.2, 456) | 100 | 88.9 | (44.3, 149) | 100 | 62.5 | (26.6, 140) |
| MiBP | 100 | 61.8 | (13.8, 284) | 100 | 49.4 | (21.9, 138) | 100 | 41.4 | (15.0, 121) |
| MEP | 100 | 28.5 | (3.28, 783) | 100 | 13.9 | (2.35, 143) | 98 | 20.0 | (2.21, 146) |
| MBzP | 84 | 1.13 | (0.262, 9.30) | 59 | 0.545 | (<LOD, 2.81) | 50 | 0.491 | (<LOD, 2.65) |
| MCNP | 37 | d | (<LOD, 0.703) | 31 | d | (<LOD, 1.55) | 28 | d | (<LOD, 0.554) |
| MCOP | 33 | d | (<LOD, 2.30) | 80 | 0.971 | (<LOD, 9.76) | 80 | 0.749 | (<LOD, 2.89) |
| MCPP | 90 | 1.31 | (0.328, 4.49) | 82 | 0.857 | (<LOD, 3.47) | 78 | 0.535 | (<LOD, 1.69) |
| MECPP | 100 | 32.3 | (9.67, 235) | 100 | 32.0 | (11.1, 168) | 100 | 31.9 | (9.81, 222) |
| MEHHP | 100 | 22.7 | (7.51, 67.5) | 100 | 21.9 | (7.93, 101) | 100 | 22.9 | (7.26, 154) |
| MEHP | 92 | 4.40 | (0.913, 38.9) | 82 | 3.39 | (0.840, 20.9) | 82 | 3.44 | (0.581, 29.2) |
| MEOHP | 100 | 14.5 | (5.49, 45.3) | 100 | 14.2 | (5.79, 74.3) | 100 | 14.4 | (5.37, 97.1) |
| ΣLMWPe | 14.4 | (4.67, 67.7) | 7.93 | (4.64, 26.7) | 7.26 | (2.92, 12.5) | |||
| ΣHMWP e | 2.70 | (0.846, 11.9) | 2.61 | (0.973, 13.3) | 2.59 | (0.845, 17.1) | |||
| ΣDEHPe | 2.55 | (0.808, 11.9) | 2.49 | (0.946, 13.2) | 2.51 | (0.817, 17.0) | |||
| ΣDBPe | 10.2 | (3.23, 34.5) | 6.42 | (3.83, 12.1) | 4.81 | (1.82, 9.31) | |||
Abbreviations: geometric mean (GM), limit of detection (LOD), mono-n-butyl phthalate (MBP), mono-isobutyl phthalate (MiBP), monoethyl phthalate (MEP), monobenzyl phthalate (MBzP), mono(carboxynonyl) phthalate (MCNP), mono(carboxyoctyl) phthalate (MCOP), mono(3-carboxypropyl) phthalate (MCPP), mono(2-ethyl-5-carboxypentyl) phthalate (MECPP), mono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP), mono(2-ethylhexyl) phthalate (MEHP), mono(2-ethyl- 5-oxohexyl) phthalate (MEOHP), low molecular weight phthalate sum (ΣLMWP), high molecular weight phthalate sum (ΣHMWP), di(2-ethylhexyl) phthalate sum (ΣDEHP), dibutyl phthalate sum (ΣDBP).
Samples with creatinine concentration ≤20 or ≥275 mg/dL were excluded.
First samples were collected during 2003-2004 for men and 1998-2002 for women.
LODs (in μg/L) are MBP: 0.4, MiBP: 0.2, MEP: 0.4, MBzP: 0.2, MCNP: 0.2, MCOP: 0.2, MCPP: 0.2, MECPP: 0.2, MEHHP: 0.2, MEHP: 0.5, MEOHP: 0.2.
GM not calculated (>50% of samples below the LOD).
Molar sums; units are nanomoles per gram creatinine.