Table 6.
Measures of reproducibility for urinary phthalate metabolite concentrations.
Phthalate Metabolite (μg/g creatinine) | Males | Females | ||||||
---|---|---|---|---|---|---|---|---|
|
|
|||||||
n | ICC1 (95% CI) | Spearman correlation coefficient2 | n | ICC1 (95% CI) | Spearman correlation coefficient2 | |||
|
||||||||
MBP | 48 | 0.30 | (0.14, 0.45) | 0.26 | 48 | 0.15 | (0.02, 0.30) | 0.24 |
MiBP | 48 | 0.21 | (0.07, 0.36) | 0.26 | 48 | 0.16 | (0.02, 0.30) | 0.06 |
MEP | 48 | 0.15 | (0.01, 0.30) | 0.17 | 48 | 0.15 | (0.02, 0.30) | 0.00 |
MBzP | 48 | 0.18 | (0.04, 0.32) | 0.05 | 48 | 0.11 | (-0.01, 0.24) | 0.08 |
MCOP | 48 | 0.013 | (-0.15, 0.09) | 0.21 | 48 | 0.09 | (-0.01, 0.21) | 0.11 |
MCPP | 48 | 0.18 | (0.05, 0.32) | 0.14 | 48 | 0.11 | (0.00, 0.24) | 0.14 |
MECPP | 48 | 0.06 | (-0.07, 0.20) | 0.21 | 48 | 0.13 | (-0.01, 0.28) | 0.25 |
MEHHP | 48 | 0.05 | (-0.08, 0.19) | 0.26 | 48 | 0.04 | (-0.09, 0.19) | 0.09 |
MEHP | 48 | 0.20 | (0.06, 0.35) | 0.43 | 48 | 0.20 | (0.06, 0.35) | 0.21 |
MEOHP | 48 | 0.04 | (-0.08, 0.19) | 0.21 | 48 | 0.04 | (-0.09, 0.18) | 0.11 |
ΣLMWP4 | 48 | 0.14 | (0.01, 0.28) | 0.22 | 48 | 0.03 | (-0.08, 0.15) | -0.02 |
ΣHMWP4 | 48 | 0.03 | (-0.10, 0.17) | 0.21 | 48 | 0.07 | (-0.06, 0.22) | 0.13 |
ΣDEHP4 | 48 | 0.05 | (-0.08, 0.20) | 0.25 | 48 | 0.07 | (-0.06, 0.22) | 0.12 |
ΣDBP4 | 48 | 0.26 | (0.12, 0.41) | 0.28 | 48 | 0.12 | (0.01, 0.25) | 0.20 |
Abbreviations: confidence interval (CI), intraclass correlation coefficient (ICC), mono-n-butyl phthalate (MBP), mono-isobutyl phthalate (MiBP), monoethyl phthalate (MEP), monobenzyl phthalate (MBzP), mono(carboxyoctyl) phthalate (MCOP), mono(3-carboxypropyl) phthalate (MCPP), mono(2-ethyl-5-carboxypentyl) phthalate (MECPP), mono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP), mono(2-ethylhexyl) phthalate (MEHP), mono(2-ethyl-5-oxohexyl) phthalate (MEOHP), low molecular weight phthalate sum (ΣLMWP), high molecular weight phthalate sum (ΣHMWP), di(2-ethylhexyl) phthalate sum (ΣDEHP), dibutyl phthalate sum (ΣDBP).
Sample 1, sample 2, and sample 3
Sample 1 and the average of samples 2 and 3
As described in the Methods, a negative estimate was obtained but replaced by an arbitrarily small value in this instance.
Molar sums; units are nanomoles per gram creatinine.