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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: JAMA Neurol. 2015 Sep 1;72(9):1013–1020. doi: 10.1001/jamaneurol.2015.0613

Table 1.

Demographics and other participant information

M ± SD Range
Age 60.7 ± 5.8 47.8 – 71.3
Insulin (μU/mL) 2.0 ± 7.0 2 – 48
Glucose (mg/dL) 94.6 ± 10.0 74 – 132
HOMA-IR 2.2 ±1.9 0.5 – 14.1
BMI 28.2 ± 5.3 18.5 – 47.3
Speed & Flexibility 0.1 ± 0.9 −2.2 – 2.4
Working Memory 0.2 ± 1.1 −2.4 – 3.2
Verbal Learning 0.2 ± 1.0 −2.5 – 1.8
Immediate Memory 0.2 ± 1.1 −2.5 – 2.9

n (%)

Women 108 (72.0%)
Family History 103 (68.7%)
APOE ε 4 Genotype 61 (40.7%)
Type 2 Diabetes 7 (4.7%)

APOE-ε4 = Apolipoprotein E ε4 genotype; BMI = Body Mass Index; HOMA-IR = Homeostatic Model Assessment of Insulin Resistance. The individual tests which loaded onto the identified factors were as follows: Rey Auditory Verbal Learning Test66 Trials 1 and 2 loaded onto Immediate Memory; Rey Auditory Verbal Learning Test66 Trials 3–5 and Delayed Recall Trial loaded onto Verbal Learning & Memory; Wechsler Adult Intelligence Scale – 3rd edition67, Digit Span forward and backward, and Letter-Numbering Sequencing subtests loaded onto Working Memory; and the interference trial from the Stroop Test68, and Trail Making Test A and B69 loaded onto Speed & Flexibility.