Table 1.
Demographics and other participant information
| M ± SD | Range | |
|---|---|---|
| Age | 60.7 ± 5.8 | 47.8 – 71.3 |
| Insulin (μU/mL) | 2.0 ± 7.0 | 2 – 48 |
| Glucose (mg/dL) | 94.6 ± 10.0 | 74 – 132 |
| HOMA-IR | 2.2 ±1.9 | 0.5 – 14.1 |
| BMI | 28.2 ± 5.3 | 18.5 – 47.3 |
| Speed & Flexibility | 0.1 ± 0.9 | −2.2 – 2.4 |
| Working Memory | 0.2 ± 1.1 | −2.4 – 3.2 |
| Verbal Learning | 0.2 ± 1.0 | −2.5 – 1.8 |
| Immediate Memory | 0.2 ± 1.1 | −2.5 – 2.9 |
|
| ||
| n (%) | ||
|
| ||
| Women | 108 (72.0%) | |
| Family History | 103 (68.7%) | |
| APOE ε 4 Genotype | 61 (40.7%) | |
| Type 2 Diabetes | 7 (4.7%) | |
APOE-ε4 = Apolipoprotein E ε4 genotype; BMI = Body Mass Index; HOMA-IR = Homeostatic Model Assessment of Insulin Resistance. The individual tests which loaded onto the identified factors were as follows: Rey Auditory Verbal Learning Test66 Trials 1 and 2 loaded onto Immediate Memory; Rey Auditory Verbal Learning Test66 Trials 3–5 and Delayed Recall Trial loaded onto Verbal Learning & Memory; Wechsler Adult Intelligence Scale – 3rd edition67, Digit Span forward and backward, and Letter-Numbering Sequencing subtests loaded onto Working Memory; and the interference trial from the Stroop Test68, and Trail Making Test A and B69 loaded onto Speed & Flexibility.