Table 1. Prevalence of positive testing for antibodies to tissue transglutaminase (tTG) type IgA and IgG*1.
| Borderline value | tTG-IgAn = 12741 | Frequency, % (95% CI) | tTG-IgA or tTG-IgG*2n = 12 741 | Frequency, % (95% CI) |
|---|---|---|---|---|
| <4 u/ml | 12581 | 98.7 (98.4 to 98.9) | 12574 | 98.6 (98.3 to 98.8) |
| ≥4 U/mL | 160 | 1.3 (1.1 to 1.6) | 167 | 1.4 (1.2 to 1.7) |
| ≥7 U/mL | 92 | 0.7 (0.6 to 0.9) | 98 | 0.8 (0.6 to 1.0) |
| >10 U/mL | 80 | 0.6 (0.5 to 0.9) | 86 | 0.7 (0.6 to 0.9) |
| >30 U/mL | 56 | 0.5 (0.3 to 0.7) | 62 | 0.5 (0.4 to 0.7) |
| ≥70 U/mL | 43 | 0.4 (0.3 to 0.5) | 47 | 0.4 (0.3 to 0.6) |
*1In children and adolescents aged between 1 and 17 years in Germany, percentages with 95% confidence intervals for various cut-off values. 7 U/mL is the borderline value stipulated by the manufacturer.
*2Includes children who tested negative for tTG-IgA but positive for tTG-IgG with IgA deficiency.
95% CI: 95% confidence interval; tTG: Tissue transglutaminase; IgA: Immunoglobulin A; IgG: Immunoglobulin G