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. 2015 Sep 16;5:14142. doi: 10.1038/srep14142

Table 1. ALDH2 protein production in the oesophagus of Aldh2 +/+ and Aldh2 –/– mice treated with or without ethanol drinking.

Groups ALDH2 level
Negative Positive
Aldh2+/+ mice
 Water 10 0
 Ethanol 4 6
Aldh2–/– mice
 Water 10 0
 Ethanol 10 0

We defined positive of ALDH2 protein levels when more than 50% of the cells were stained with anti-ALDH2 antibody in the basal and parabasal layers of the oesophageal epithelium. Ethanol drinking induced ALDH2 in the oesophageal epithelium in 6 out of 10 Aldh2+/+ mice, whereas there was no induction in the water group of Aldh2+/+ mice (p = 0.011 by Fisher’s exact test).