Fig. 4.

The effect of traumatic brain injury (TBI) on Veterinary coma scale (VCS) in different groups (n = 7 in each group). The data are represented as mean±SEM. *** P < 0.001; at 4 and 24 h after TBI for TBI vs sham ,### P < 0.001; at 4 and 24 h after TBI for TBI + E₂vs TBI and TBI + OIL groups (A).^*** P < 0.001; at 4 and 24 h after TBI for TBI + ICI + E₂vs TBI + E₂ and TBI + DMSO + E₂(B). TBI, traumatic brain injury; E₂, estradiol; ICI, ICI 182,780