Table 3.
Mean values of lipids levels, FBS, and LCAT activity among genotypes
| rs5923 polymorphism |
Total
|
|
Low HDL
|
|
High HDL
|
||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| CC | CT |
P
value |
CC | CT | P value | CC | CT | P value | |||
| HDL-C levels (mg/dl) | 50 ± 24 | 35 ± 18 | 0.02 | 28 ± 3 | 26 ± 2 | 0.10 | 74 ± 10 | 70 ± 4 | 0.41 | ||
| TG levels (mg/dl) | 171 ± 166 | 239 ±182 | 0.14 | 106 ± 15 | 105 ± 21 | 0.76 | 81 ± 44 | 54 ± 12 | 0.30 | ||
| LDL levels (mg/dl) | 98 ± 32 | 99 ± 36 | 0.93 | 250 ± 192 | 285 ± 175 | 0.56 | 106 ± 35 | 97 ± 49 | 0.69 | ||
| TC levels (mg/dl) | 183 ± 48 | 173 ± 43 | 0.46 | 91 ± 27 | 100 ± 35 | 0.38 | 197 ± 43 | 178 ± 45 | 0.46 | ||
| FBS (mg/dl) | 99 ± 21 | 111 ± 48 | 0.08 | 170 ± 49 | 172 ± 45 | 0.91 | 92 ± 8 | 83 ± 4 | 0.08 | ||
| BMI (kg/m2) | 25 ± 3 | 26 ± 3 | 0.13 | 105 ± 27 | 118 ± 52 | 0.18 | 23 ± 3 | 24 ± 3 | 0.67 | ||
| LCAT activity (nmol /ml/h) | 105 ± 14 | 103 ± 19 | 0.80 | 26 ± 3 | 27 ± 2 | 0.48 | 103 ± 13 | 98 ± 12 | 0.57 | ||
HDL-C, high-density lipoprotein cholesterol; LCAT, lecithin: cholesterol acyltransferase; LDL-L, low-density lipoprotein; TC, total cholesterol; TG, triglycerides ; FBS, fasting blood glucose. Distribution of mean values with standard deviations of HDL-C levels, LCAT activity among LCAT genotypes