Table 2.
De Novo Mutations Originating from Parental Mosaicism
Genomic Location | Gene | OMIM Accession Number | Gene Location | Origin | Total Reads (ADS) | Variant Reads | p Valuea |
---|---|---|---|---|---|---|---|
chr13:78303535A>T | SLAIN1 | 610491 | intron | father | 31,470 | 6.15% | <0.001 |
chr18:25210178C>T | – | – | intergenic | father | 34,149 | 2.56% | <0.001 |
chr5:11327458C>T | CTNND2 | 604275 | intron | mother | 12,754 | 5.25% | <0.001 |
chr5:147855052G>A | HTR4 | 602164 | intron | father | 20,927 | 0.22% | <0.05 |
p values were corrected for multiple testing by Bonferroni correction.