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. 2015 Sep 16;16:83. doi: 10.1186/s12881-015-0223-9

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© Shu et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Clinical examination. a Pure tone audiogram showed bilateral downward-sloping moderate to severe hearing loss in one patient with Usher syndrome (F1-II-1); b Tympanometry examination demonstrated the normal functions of middle ear and eardrum in the F1-II-1 proband; c Fundoscopy of the F1-II-1 patient revealed symptoms typical of retinitis pigmentosa. d OCT of the F1-II-1 patient showed that retinal thickness was diminished