Table 1.
Disorders produced or aggravated by low vitamin D statusa
| Disorder | Strength of Evidence |
|---|---|
| Osteoporosis | ++++ |
| Falls | ++++ |
| Type 1 diabetes | ++ |
| Cancer | ++++ |
| Autoimmune diseases | ++ |
| Hypertension | +++ |
| Periodontal disease | ++++ |
| Multiple Sclerosis | ++ |
| Susceptibility/poor response to infection | ++++ |
| Osteoarthritis | ++ |
a
++++, strong evidence including one or more randomized trials; +++, strong and consistent epidemiologic evidence, without, however, evidence from randomized trials; ++ and +, less strong evidence that is nevertheless suggestive.