Table 4.
Main studies evaluating the relationships between ACE I/D genotypes and response to ARA therapy in non diabetic renal disease
| Redon et al. (61), 2005 | Coto et al. (60), 2005a | Park et al. (62), 2006 | |
|---|---|---|---|
| Ethnicity | White | White | Asian |
| No. of patients | 206 | 37 | 99 |
| Follow-up (yr) | 1 | 0.3 | 055 |
| Patient characteristics | Essential hypertension, microalbuminuria | Chronic nephropathy | Overt proteinuria |
| Baseline characteristics of genotype groups | No data on age and gender | ? | Comparable |
| Treatment in genotype groups | ? | ? | ? |
| Adjustments for relevant covariates | ? | ? | ? |
| Effect of ACE inhibitor therapy | Comparable UAE reduction in the 3 genotypes | Comparable UAE reduction in the 3 genotypes | Comparable proteinuria reduction in the 3 genotypes |
?, insufficient information.
a
Data retrieved from the English abstract.