Table 2.

Suggested contraindications to oral sodium phosphate administration

Absolute contraindications

Estimated glomerular filtration rate <60 ml/min

Significant kidney disease with preserved GFR (e.g., nephrotic syndrome)

Preexisting hyperphosphatemia of any cause

Clinically significant congestive heart failure or cardiomyopathy

Clinically significant cirrhosis and/or ascites

Gastrointestinal disease, as detailed on package label including obstruction, megacolon, perforation, ileus, inflammatory bowel disease

Hypersensitivity to the ingredients

Relative contraindications

Age <18 or >60 to 70 or clinically significant debilitation

Use of diuretics, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, or nonsteroidal anti-inflammatory drugs, especially if in combination

Dehydration or risk for dehydration (e.g., nausea, vomiting, diarrhea, low salt diet, inability to take adequate oral fluids).

Uncorrected electrolyte abnormalities

Cardiac disease as detailed on package labeling, including recent MI, prolonged QT interval, or drugs that prolong interval, arrhythmia, unstable angina.

Pregnancy or nursing a child, as per package labeling.