FIGURE 4:

Wound healing is accelerated in rodless plectin mice. (A) Hematoxylin and eosin–stained sections depicting wound closure in wild-type and rodless plectin mice on day 3 after wounding. The outline of the epidermal lip is indicated by a dotted line. Scale bar, 100 μm. (B) Boxplot showing the length of the epidermal lip in wild-type and rodless plectin mice on day 3 after wounding. The data represent 27 wild-type (99 wounds) and 22 rodless plectin mice (81 wounds) pooled from four independent experiments. Statistical significance was determined using the Student's t test. *p < 0.01. (C) Cell proliferation in the epidermal lip was quantified by determining the average number of Ki67⁺ cells/mm in the wounds of four wild-type and four rodless plectin mice. Error bars represent the SD.