Table 2. Percent drug remaining, diameter and zeta potential in CAP/NPs stored at various temperatures (4 °C/65% RH, 25 °C/65% RH, and 40 °C/75% RH) for 3 months.
Time (month) | Temperature (RH) | %Drug remained | Diameter (nm) | Zeta potential (mV) |
---|---|---|---|---|
0 | 4 °C/65% | 100 | 82.52±0.51 | −24.67±4.3 |
1 | 4 °C/65% | 99.67 | 84.17±0.91 | −23.63±5.4 |
2 | 4 °C/65% | 99.48 | 86.79±1.06 | −24.01±3.6 |
3 | 4 °C/65% | 99.15 | 86.46±0.72 | −23.45±4.6 |
0 | 25 °C/65% | 100 | 82.52±0.51 | −24.67±4.3 |
1 | 25 °C/65% | 99.59 | 83.52±0.74 | −23.21±5.6 |
2 | 25 °C/65% | 99.32 | 86.42±0.83 | −22.81±5.2 |
3 | 25 °C/65% | 99.10 | 87.05±0.94 | −23.79±3.7 |
0 | 40 °C/75% | 100 | 82.52±0.51 | −24.67±4.3 |
1 | 40 °C/75% | 99.43 | 85.36±1.13 | −23.15±3.5 |
2 | 40 °C/75% | 98.42 | 87.83±0.97 | −23.79±4.8 |
3 | 40 °C/75% | 97.76 | 87.50±0.75 | −24.46±5.3 |