IHC findings and protein expression of glycogen-like peptide-1 receptor (GLP-1R) in kidney at 72 h after IR injury (n=8 for each group). (A–D) The IHC stain (200×) identifying the GLP-1R (brown color) in kidney parenchyma among four groups at 72 h (A–D) after IR procedure. (E) cP<0.01 vs sham control, bP=0.05 vs other groups. Scale bars in right lower corner represent 50 μm. (F) The protein expression of GLP-1R in kidney parenchyma among four group at 72 h after acute IR injury, cP<0.01 vs sham control, bP=0.05 vs other groups. All statistical analyses using one-way ANOVA, followed by Bonferroni multiple comparison post hoc test. SC, sham control; KIR, kidney ischemia reperfusion; Sita, sitagliptin.